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News

Lab Meeting Weekly Update

  • Christian Micille updated the lab team on his successes in his mouse colony!
  • John updated the lab members on his current project
  • Dr. Igor Efimov visited Stockholm last week for the Leducq Foundation Project
  • New team members will join very soon…keep checking back for more news from our new member!

Papers​ ​and​ ​projects​ ​to​ ​look​ ​out​ ​for​ ​in​ ​the​ ​future:

●”Transmural Repolarization” by Bans Boukens

●Purkinje fibers paper by Katherine Holzem

Lab Meeting Weekly Update

  • Jaclyn​ ​Brennan’s​ ​Presentation​ ​Over​ ​the​ ​Article: 
    • Olivas​ ​A,​ ​Gardner​ ​RT,​ ​Wang​ ​L,​ ​Ripplinger​ ​CM,​ ​Woodward​ ​WR,​ ​Habecker​ ​BA. 

Myocardial​ ​Infarction​ ​Causes​ ​Transient​ ​Cholinergic​ ​Transdifferentiation​ ​of Cardiac​ ​Sympathetic​ ​Nerves​ ​via​ ​gp130.​ ​J​ ​Neurosci.​ ​2016​ ​Jan​ ​13;36(2):479-88. doi:​ ​10.1523/JNEUROSCI.3556-15.2016.​ ​PubMed​ ​PMID:​ ​26758839;​ ​PubMed Central​ ​PMCID:​ ​PMC4710771. 

Lab Meeting Weekly Update

  • The website (efimovlab.org) has new features! You can now see and read about our amazing staff and graduate students, and you will soon be able to read about the undergraduates working in the lab - be on the lookout!
  • Christian Micille updated the lab on some exciting news on his mouse colonies: the lab has a numerous amount of different type of mice ready to be genotyped!

Papers and projects to look out for in the future:

Lab Meeting Weekly Update

  • Song Zhang will be visiting the lab within the following week in order to possibly buy a new, exciting lab camera!
  • Dr. Aras continued to give updates on his rabbit heart study, which involves cardiac mechanics and optical mapping.
  • Devon Guerrelli gave updates on her CLARITY study.

Papers and projects to look out for in the future:

Lab Meeting Weekly Update

 

  • Dr. Aras presented updates on his canine AF study. 

  • Dr. Efimov shared an information research video in which a research team at the University of Wisconsin-Madison demonstrates a method for high-resolution optical mapping of the mouse sino-atrial node.

Some of the staff are in the final stages of publishing papers and projects:

  • Chaoyi Kang's IKs/IKr paper

Medical Technology of the Future

We are excited to announce the publication of our latest work in Nature Biomedical Engineering. In collaboration with the John Rogers' Lab, we validated their novel electrode design by simultaneously recording while collecting optically mapping images in an in-vitro Langendorff perfused rabbit heart. This device platform overcomes issues associated with chronic implantation of metal oxide electrodes (e.g. intrusion of biofluids into underlying electronics and current leakage).

EFIMOV LAB REPRESENTS AT GWU SEAS R&D SHOWCASE

Yesterday evening was the yearly GWU SEAS R&D Showcase. Students from all of GWU's engineering disciplines prepared posters of their work and were judged by a panel of investigators and volunteers from industry. We would like to congratulate Chris Gloschat for being awarded 3rd Place Best Experimental Poster and Jaclyn Brennan for being awarded a Runner-Up Student Travel Award!

Leducq Foundation funded our transatlantic network of excellence: RHYTHM!

Our transatlantic network consisting of 6 universities received funding from the Leducq Foundation. Our project is titled Repolarization HeterogeneitY imaging for personalised Therapy of Heart arrhythMia (RHYTHM). Project was among only 5 funded proposals selected from 120 submitted. Project description and participants on the Leducq Foundation web-site: https://www.fondationleducq.org/network/repolarization-heterogeneity-ima...

The Heart of the Matter

Since 1958, average life expectancy in the US has increased by 10 years. According to Igor Efimov, the inaugural chair of GW’s Department of Biomedical Engineering and the Alisann and Terry Collins Professor of Biomedical Engineering, the 68 percent reduction in the mortality rate from heart disease during the same period is a huge contributor to this remarkable gain in life expectancy.

That said, heart disease still remains the country’s number one killer, and Dr. Efimov has dedicated his life’s work to better understanding and developing devices to treat it.

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