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Igor Efimov Awarded $2.5 million R01 Grant for the project “High-Definition Conformal Electronics for VT/VF”

The National Institutes of Health National Heart, Lung, and Blood Institute has awarded Dr. Igor Efimov (BME) a four-year, $2.5 million R01 grant for the project “High-Definition Conformal Electronics for VT/VF.” Ventricular fibrillation (rapid and irregular heart beat) is responsible for 300,000 sudden cardiac deaths (SCD) annually in the United States. Current treatment options have limited efficacy and are hampered by serious side effects. Future development of an effective therapy requires detailed knowledge of the disorganized electrical waves in the fibrillating human ventricles.

Two of Efimov's undergraduate students publish open-source optocardiography system in Nature Scientific Reports

Brianna Cathey (B.S. '19) and Sofian Obaid (B.S. '18, PhD) published a paper titled Open-Source Multiparametric Optocardiography in Nature Scientific Reports. This paper presents a low-cost, customizable 3D-printed optical mapping system. Optical mapping is a leading tool used in cardiac electrophysiology to study the mechanisms of arrythmias. Despite it's crucial role in these discoveries, the commercial cost of the necessary mechanical equipment prevents widespread implementation.

Dr. Efimov named a Fellow of the National Academy of Inventors

The National Academy of Inventors (NAI) announced on December 11 that it has elected Dr. Igor Efimov to the rank of NAI Fellow.  Election to NAI Fellow status is the highest professional distinction accorded to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society.  Dr.

Sharon George and Rose Yin receive AHA Fellowships

The BME department congratulates postdoctoral fellow Dr. Sharon George and doctoral student Rose Yin, who have both been awarded fellowships from the American Heart Association to study in Dr. Igor Efimov's laboratory.  Sharon has been awarded a two-year post-doctoral fellowship to study the differential roles of p38 MAPK isoforms in Doxorubicin-induced cardiotoxicity, and Rose has been awarded a two-year pre-doctoral fellowship to study selective optical defibrillation of the excitable gap to terminate ventricular arrhythmias in mice.

Faculty and students attend BMES 50th Annual Conference

  • The BME Department was well represented at the BMES (Biomedical Engineering Society) 50th Annual Conference, held October 17-20 in Atlanta, GA.  The department and the SEAS Office of Graduate Admissions and Student Services also hosted a booth to share information about BME graduate programs and research with prospective students.
  • Congratulations to all who presented from our lab:
    • Kedar Aras, “Electrophysiological Profile of Human Right Ventricular Outflow Tract”

Anna Gams wins APS Abstract Travel Award

BME doctoral student Anna Gams won The American Physiological Society Abstract Travel Award at the 2018 APS Conference on Cardiovascular, Renal, and Metabolic Diseases: Sex-Specific Implications for Physiology.  The conference was held September 30 – October 3 in Knoxville, TN.  Anna’s research was titled “Sex Differences in Healthy Human Heart Revealed by Cap Analysis Gene Expression.”Please see the conference poster to read more about Anna's research.

Lab Meeting Weekly Update

  • Dr. Efimov has been traveling the past couple weeks. He visited the University of Arkansas to review their graduate Biomedical Engineering programs and visited Taiwan for the Asia Pacific Heart Rhythm Society annual sessions.
  • Lilly provided a lab update on the doxorubicin project. She has been working with Sharon on the histology to determine any structural remodeling of the heart.
  • Congratulations to all who presented at the BMES Conference in Atlanta this past week:
    • Kedar Aras, “Electrophysiological Profile of Human Right Ventricular Outflow Tract”

Visit to Libin Cardiovascular Institute of Alberta

April 16 and 17 I visited Libin Cardiovascular Institute of Alberta at the University of Calgary, Canada. Snow storm prevented my visit last year, and another snow storm tried to stop me this year, all flights via Minneapolis were cancelled except one! It was an honor to present the Dr. E. R. Smith Lecture in Cardiovascular Research, which was the keynote lecture at the annual Libin Cardiovascular Institute's Tine Haworth Research Day 2018. My lecture was titled "New Technology for Human Heart Physiology".

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