Publications

2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003

2017

  • Matkovich SJ, Al Khiami B, Efimov IR, Evans S, Vader J, Jain A, Brownstein BH, Hotchkiss RS, Mann DL. Widespread Down-Regulation of Cardiac Mitochondrial and Sarcomeric Genes in Patients With Sepsis. Crit Care Med. 2017 Jan 6. doi: 10.1097/CCM.0000000000002207. [Epub ahead of print] PubMed PMID: 28067713.[PubMed]

    2016

    • Holzem KM, Vinnakota KC, Ravikumar VK, Madden EJ, Ewald GA, Dikranian K, Beard DA, Efimov IR. Mitochondrial structure and function are not different between non-failing donor and end-stage failing human hearts. FASEB J, 2016, in press. [PubMed]
    • Ng FS, Efimov IR. Letter by Ng and Efimov Regarding Article, "Electrophysiological Effects of Selective Atrial Coronary Artery Occlusion in Humans". Circulation. 2016 Nov 1;134(18):e397-e398. PubMed PMID: 27799265; PubMed Central PMCID: PMC5179040. [PubMed]
    • Holzem KM, Gomez JF, Glukhov AV, Madden EJ, Koppel AC, Ewald GA, Trenor B, Efimov IR. Reduced response to IKr blockade and altered hERG1a/1b stoichiometry in human heart failure. J Mol Cell Cardiol. 2016 Jul;96:82-92. doi: 10.1016/j.yjmcc.2015.06.008. PubMed PMID: 26093152; PubMed Central PMCID: PMC4683114. [PubMed]
    • Kay MW, Efimov IR. Optical Mapping of Cardiac Electromechanics. Biophys J. 2016 Jul 26;111(2):269-70. doi: 10.1016/j.bpj.2016.04.052. PubMed PMID: 27463128; PubMed Central PMCID: PMC4968416. [PubMed]
    • Nadadur RD, Broman MT, Boukens B, Mazurek SR, Yang X, van den Boogaard M, Bekeny J, Gadek M, Ward T, Zhang M, et al. Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm. Sci Transl Med. 2016 Aug 31;8(354):354ra115. doi: 10.1126/scitranslmed.aaf4891. PubMed PMID: 27582060; PubMed Central PMCID: PMC5266594. [PubMed]
    • Haissaguerre M, Shah AJ, Cochet H, Hocini M, Dubois R, Efimov I, Vigmond E, Bernus O, Trayanova N. Intermittent drivers anchoring to structural heterogeneities as a major pathophysiological mechanism of human persistent atrial fibrillation. J Physiol. 2016 May 1;594(9):2387-98. doi: 10.1113/JP270617. PubMed PMID: 26890861; PubMed Central PMCID: PMC4850206. [PubMed]
    • Gloschat CR, Koppel AC, Aras KK, Brennan JA, Holzem KM, Efimov IR. Arrhythmogenic and metabolic remodeling of failing human heart. J Physiol. 2016 Mar 28. doi: 10.1113/JP271992. [PubMed]
    • Jaimes R 3rd, Walton RD, Pasdois PL, Bernus O, Efimov IR, Kay MW. A Technical Review of Optical Mapping of Intracellular Calcium within Myocardial Tissue. Am J Physiol Heart Circ Physiol. 2016 Mar 25:ajpheart.00665.2015. doi: 10.1152/ajpheart.00665.2015. [PubMed]
    • Koh A, Gutbrod SR, Meyers JD, Lu C, Webb RC, Shin G, Li Y, Kang SK, Huang Y, Efimov IR, Rogers JA. Ultrathin Injectable Sensors: Ultrathin Injectable Sensors of Temperature, Thermal Conductivity, and Heat Capacity for Cardiac Ablation Monitoring (Adv. Healthcare Mater. 3/2016). Adv Healthc Mater. 2016 Feb;5(3):394. doi: 10.1002/adhm.201670015. [PubMed]
    • Koh A, Gutbrod SR, Meyers JD, Lu C, Webb RC, Shin G, Li Y, Kang SK, Huang Y, Efimov IR, Rogers JA. Ultrathin Injectable Sensors of Temperature, Thermal Conductivity, and Heat Capacity for Cardiac Ablation Monitoring. Adv Healthc Mater. 2016 Feb;5(3):373-81. doi: 10.1002/adhm.201500451. Epub 2015 Dec 9. [PubMed]

    2015

    • Holzem KM, Marmerstein JT, Madden EJ, Efimov IR. Diet-induced obesity promotes altered remodeling and exacerbated cardiac hypertrophy following pressure overload. Physiol Rep. 2015 Aug;3(8). pii: e12489. doi: 10.14814/phy2.12489. [PubMed]
    • Boukens BJ, Gutbrod SR, Efimov IR. Imaging of Ventricular Fibrillation and Defibrillation: The Virtual Electrode Hypothesis. Adv Exp Med Biol. 2015;859:343-65. doi: 10.1007/978-3-319-17641-3_14. Review. PMID: 26238060 [PubMed]
    • Boukens BJ, Sulkin MS, Gloschat CR, Ng FS, Vigmond EJ, Efimov IR. Transmural APD gradient synchronizes repolarization in the human left ventricular wall. Cardiovasc Res. 2015 Oct 1;108(1):188-96. doi: 10.1093/cvr/cvv202. Epub 2015 Jul 24. PMID: 26209251 [PubMed]
    • Holzem KM, Gomez JF, Glukhov AV, Madden EJ, Koppel AC, Ewald GA, Trenor B, Efimov IR. Reduced response to IKr blockade and altered hERG1a/1b stoichiometry in human heart failure. J Mol Cell Cardiol. 2015 Jun 17. pii: S0022-2828(15)00194-7. doi: 10.1016/j.yjmcc.2015.06.008. PMID: 26093152[PubMed]
    • Ripplinger CM, Efimov IR.Dual Vm/Ca imaging of premature ventricular contractions: bridging the gap of anatomical scales. Circ Arrhythm Electrophysiol. 2015 Jun;8(3):529-30. doi: 10.1161/CIRCEP.115.002916. PMID: 26082526 [PubMed]
    • Doshi AN, Walton RD, Krul SP, de Groot JR, Bernus O, Efimov IR, Boukens BJ, Coronel R. Feasibility of a semi-automated method for cardiac conduction velocity analysis of high-resolution activation maps. Comput Biol Med. 2015 Oct 1;65:177-83. doi: 10.1016/j.compbiomed.2015.05.008. Epub 2015 May 21.PMID: 26045101 [PubMed]
    • Child N, Bishop MJ, Hanson B, Coronel R, Opthof T, Boukens BJ, Walton RD, Efimov IR, Bostock J, Hill Y, Rinaldi CA, Razavi R, Gill J, Taggart P. An activation-repolarization time metric to predict localized regions of high susceptibility to reentry. Heart Rhythm. 2015 Jul;12(7):1644-53. doi: 10.1016/j.hrthm.2015.04.013. Epub 2015 Apr 9. PMID: 25863160 [PubMed]
    • Kurian T, Doshi A, Kessman P, Nguyen B, Edwards J, Pieper S, Efimov I, Janardhan AH, Sanchez M. Rotors in patients with persistent atrial fibrillation: case report of a left atrial appendage rotor identified by a novel computational mapping algorithm integrated into 3-dimensional mapping and termination of atrial fibrillation with ablation. Card Electrophysiol Clin. 2015 Mar;7(1):157-63. doi: 10.1016/j.ccep.2014.11.009. Epub 2014 Dec 18. PMID: 25784031 [PubMed]
    • Bear L, Cuculich PS, Bernus O, Efimov I, Dubois R. Introduction to noninvasive cardiac mapping. Card Electrophysiol Clin. 2015 Mar;7(1):1-16. doi: 10.1016/j.ccep.2014.11.015. Review. PMID: 25784020 [PubMed]
    • Gutbrod SR, Walton R, Gilbert S, Meillet V, Jaïs P, Hocini M, Haïssaguerre M, Dubois R, Bernus O, Efimov IR. Quantification of the transmural dynamics of atrial fibrillation by simultaneous endocardial and epicardial optical mapping in an acute sheep model. Circ Arrhythm Electrophysiol. 2015 Apr;8(2):456-65. doi: 10.1161/CIRCEP.114.002545. Epub 2015 Feb 24. PMID: 25713215 [PubMed]
    • Lang D, Holzem K, Kang C, Xiao M, Hwang HJ, Ewald GA, Yamada KA, Efimov IR. Arrhythmogenic remodeling of β2 versus β1 adrenergic signaling in the human failing heart. Circ Arrhythm Electrophysiol. 2015 Apr;8(2):409-19. doi: 10.1161/CIRCEP.114.002065. Epub 2015 Feb 11. PMID: 25673629 [PubMed]
    • Xu L, Gutbrod SR, Ma Y, Petrossians A, Liu Y, Webb RC, Fan JA, Yang Z, Xu R, Whalen JJ 3rd, Weiland JD, Huang Y, Efimov IR, Rogers JA. Materials and fractal designs for 3D multifunctional integumentary membranes with capabilities in cardiac electrotherapy. Adv Mater. 2015 Mar 11;27(10):1731-7. doi: 10.1002/adma.201405017. Epub 2015 Jan 12. PMID: 25641076 [PubMed]
    • Gillers BS, Chiplunkar A, Aly H, Valenta T, Basler K, Christoffels VM, Efimov IR, Boukens BJ, Rentschler S. Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties. Circ Res. 2015 Jan 30;116(3):398-406. doi: 10.1161/CIRCRESAHA.116.304731. Epub 2014 Nov 6. PMID: 25599332 [PubMed]
    • Wu Z, Kumon RE, Laughner JI, Efimov IR, Deng CX. Electrophysiological Changes Correlated with Temperature Increases Induced by High-Intensity Focused Ultrasound Ablation. Ultrasound Med Biol. 2015 Feb;41(2):432-48. doi: 10.1016/j.ultrasmedbio.2014.09.009. Epub 2014 Dec 13. PMID: 25516446. [PubMed]

    2014

    • Holzem KM, Madden EJ, Efimov IR. Human cardiac systems electrophysiology and arrhythmogenesis: iteration of experiment and computation. Europace, 2014 Nov;16 Suppl 4:iv77-iv85. doi: 10.1093/europace/euu264. PMID: 25362174. [PubMed]
    • Gutbrod SR, Sulkin MS, Rogers JA, Efimov IR. Patient-Specific Flexible and Stretchable Devices for Cardiac Diagnostics and Therapy, Progress in Biophysics and Molecular Biology, 2014 Aug;115(2-3):244-51. doi: 10.1016/j.pbiomolbio.2014.07.011. Epub 2014 Aug 5. PMID: 25106701. [PubMed]
    • Xu L, Gutbrod SR, Bonifas AP, Su Y, Sulkin MS, Lu N, Chung HJ, Jang KI, Liu Z, Ying M, Lu C, Webb RC, Kim JS, Laughner JI, Cheng H, Liu Y, Ameen A, Jeong JW, Kim GT, Huang Y, Efimov IR, Rogers JA. 3D multifunctional integumentary membranes for spatiotemporal cardiac measurements and stimulation across the entire epicardium. Nat Commun. 2014 Feb 25;5:3329. doi: 10.1038/ncomms4329. PMID: 24569383. [PubMed] [PDF]
    • Chung HJ, Sulkin MS, Kim JS, Goudeseune C, Chao HY, Song JW, Yang SY, Hsu YY, Ghaffari R, Efimov IR, Rogers JA. Stretchable, Multiplexed pH Sensors With Demonstrations on Rabbit and Human Hearts Undergoing Ischemia. Adv Healthc Mater. 2014 Jan;3(1):59-68. doi: 10.1002/adhm.201300124. Epub 2013 Jul 19. PMID: 23868871. [PubMed]
    • Arakel EC, Brandenburg S, Uchida K, Zhang H, Lin YW, Kohl T, Schrul B, Sulkin MS, Efimov IR, Nichols CG, Lehnart SE, Schwappach B. Tuning the electrical properties of the heart by differential trafficking of KATP ion channel complexes. J Cell Sci. 2014 May 1;127(Pt 9):2106-19. doi: 10.1242/jcs.141440. Epub 2014 Feb 25. PMID: 24569881. [PubMed]
    • Rutledge CA, Ng FS, Sulkin MS, Greener ID, Sergeyenko AM, Liu H, Gemel J, Beyer EC, Sovari AA, Efimov IR, Dudley SC. c-Src Kinase Inhibition Reduces Arrhythmia Inducibility and Connexin43 Dysregulation After Myocardial Infarction. J Am Coll Cardiol. 2014 Mar 11;63(9):928-34. doi: 10.1016/j.jacc.2013.10.081. Epub 2014 Jan 8. PMID: 24361364. [PubMed]
    • Gutbrod SR, Efimov IR. A shocking past: a walk through generations of defibrillation development. IEEE Trans Biomed Eng. 2014 May;61(5):1466-73. doi: 10.1109/TBME.2014.2301035. PMID: 24759279. [PubMed]
    • Gutbrod SR, Sulkin MS, Rogers JA, Efimov IR. Patient-specific flexible and stretchable devices for cardiac diagnostics and therapy. Prog Biophys Mol Biol. 2014 Aug;115(2-3):244-51. doi: 10.1016/j.pbiomolbio.2014.07.011. Epub 2014 Aug 5. PMID: 25106701. [PubMed]
    • Ng FS, Holzem KM, Koppel AC, Janks D, Gordon F, Wit AL, Peters NS, Efimov IR. Adverse Remodeling of the Electrophysiological Response to Ischemia-Reperfusion in Human Heart Failure Is Associated with Remodeling of Metabolic Gene Expression. Circ Arrhythm Electrophysiol. 2014 Oct;7(5):875-82. doi: 10.1161/CIRCEP.113.001477. Epub 2014 Aug 11. PMID: 25114062. [PubMed]
    • Boukens B, Efimov I. A Century of Optocardiography. IEEE Rev Biomed Eng. 2014;7:115-25. doi: 10.1109/RBME.2013.2286296. Epub 2013 Oct 23. PMID: 24158521. [PubMed]
    • Sulkin MS, Yang F, Holzem KM, Van Leer B, Bugge C, Laughner JI, Green K, Efimov IR. Nanoscale three-dimensional imaging of the human myocyte. J Struct Biol. 2014 Oct;188(1):55-60. doi: 10.1016/j.jsb.2014.08.005. Epub 2014 Aug 23. PMID: 25160725 [PubMed]
    • Janardhan AH, Gutbrod SR, Li W, Lang D, Schuessler RB, Efimov IR. Multi-Stage Electrotherapy Delivered Through Chronically Implanted Leads Terminates Atrial Fibrillation with Lower Energy than a Single Biphasic Shock. J Am Coll Cardiol. 2014 Jan 7-14;63(1):40-8. doi: 10.1016/j.jacc.2013.07.098. Epub 2013 Sep 26. PMID: 24076284. [PubMed]
    • Sulkin MS, Boukens BJ, Tetlow M, Gutbrod SR, Ng FS, Efimov IR. Mitochondrial depolarization and electrophysiological changes during ischemia in the rabbit and human heart. Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1178-86. doi: 10.1152/ajpheart.00437.2014. Epub 2014 Aug 15. PMID: 25128175. [PubMed]

    2013

    • Ambrosi CM, Yamada KA, Nerbonne JM, Efimov IR. Gender differences in electrophysiological gene expression in failing and non-failing human hearts. PLoS One. 2013;8(1):e54635. doi: 10.1371/journal.pone.0054635. Epub 2013 Jan 23. PMID: 23355885. [PubMed]
    • Takasu O, Gaut JP, Watanabe E, To K, Fagley RE, Sato B, Jarman S, Efimov IR, Janks DL, Srivastava A, Bhayani SB, Drewry A, Swanson PE, Hotchkiss RS. Mechanisms of cardiac and renal dysfunction in patients dying of sepsis. Am J Respir Crit Care Med. 2013 Mar 1;187(5):509-17. doi: 10.1164/rccm.201211-1983OC. Epub 2013 Jan 24. PMID: 23348975. [PubMed]
    • Glukhov AV, Uchida K, Efimov IR, Nichols CG. Functional roles of KATP channel subunits in metabolic inhibition. J Mol Cell Cardiol. 2013 Sep;62:90-8. doi: 10.1016/j.yjmcc.2013.04.016. Epub 2013 Apr 23. PMID: 23624089. [PubMed]
    • Smith AW, Hoyne JD, Nguyen PK, McCreedy DA, Aly H, Efimov IR, Rentschler S, Elbert DL. Direct reprogramming of mouse fibroblasts to cardiomyocyte-like cells using Yamanaka factors on engineered poly(ethylene glycol) (PEG) hydrogels. Biomaterials. 2013 Sep;34(28):6559-71. doi: 10.1016/j.biomaterials.2013.05.050. Epub 2013 Jun 14. PMID: 23773820 [PubMed]
    • Liu M, Gu L, Sulkin MS, Liu H, Jeong EM, Greener I, Xie A, Efimov IR, Dudley SC Jr. Mitochondrial dysfunction causing cardiac sodium channel downregulation in cardiomyopathy. J Mol Cell Cardiol. 2013 Jan;54:25-34. doi: 10.1016/j.yjmcc.2012.10.011. Epub 2012 Nov 1. PMID: 23123323. [PubMed]
    • Rutledge CA, Ng FS, Sulkin MS, Greener ID, Sergeyenko AM, Liu H, Gemel J, Beyer EC, Sovari AA, Efimov IR, Dudley SC. c-Src Kinase Inhibition Reduces Arrhythmia Inducibility and Connexin43 Dysregulation after Myocardial Infarction. J Am Coll Cardiol. 2014 Mar 11;63(9):928-34. doi: 10.1016/j.jacc.2013.10.081. Epub 2014 Jan 8. PMID: 24361364. [PubMed]
    • Laughner JI, Marrus SB, Zellmer ER, Weinheimer CJ, MacEwan MR, Cui SX, Nerbonne JM, Efimov IR. A fully implantable pacemaker for the mouse: from battery to wireless power. PLoS One. 2013 Oct 23;8(10):e76291. doi: 10.1371/journal.pone.0076291. PMID: 24194832. [PubMed]
    • Wang Y, Laughner JI, Efimov IR, Zhang S. 3D absolute shape measurement of live rabbit hearts with a superfast two-frequency phase-shifting technique. Opt Express. 2013 Mar 11;21(5):5822-32. doi: 10.1364/OE.21.005822. PMID: 23482151. [PubMed]
    • Walmsley J, Rodriguez JF, Mirams GR, Burrage K, Efimov IR, Rodriguez B. mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a population-based simulation study. PLoS One. 2013;8(2):e56359. doi: 10.1371/journal.pone.0056359. Epub 2013 Feb 20. PMID: 23437117. [PubMed]
    • Sulkin MS, Widder E, Shao C, Holzem KM, Gloschat C, Gutbrod SR, Efimov IR. Three-dimensional printing physiology laboratory technology. Am J Physiol Heart Circ Physiol. 2013 Dec;305(11):H1569-73. doi: 10.1152/ajpheart.00599.2013. Epub 2013 Sep 16. PMID: 24043254. [PubMed]
    • Luo M, Guan X, Luczak ED, Lang D, Kutschke W, Gao Z, Yang J, Glynn P, Sossalla S, Swaminathan PD, Weiss RM, Yang B, Rokita AG, Maier LS, Efimov IR, Hund TJ, Anderson ME. Diabetes increases mortality after myocardial infarction by oxidizing CaMKII. J Clin Invest. 2013 Mar 1;123(3):1262-74. doi: 10.1172/JCI65268. Epub 2013 Feb 15. PMID: 23426181. [PubMed]
    • Gutbrod SR, Efimov IR. Two centuries of resuscitation. J Am Coll Cardiol. 2013 Dec 3;62(22):2110-1. doi: 10.1016/j.jacc.2013.07.026. Epub 2013 Aug 7. PMID: 23933547. [PubMed]

    2012

    • Laughner JI, Ng FS, Sulkin MS, Arthur MA, Efimov IR. Processing and Analysis of Cardiac Optical Mapping Data Obtained with Potentiometric Dyes. Am J Physiol Heart Circ Physiol. 2012 Oct 1;303(7):H753-65. doi: 10.1152/ajpheart.00404.2012. Epub 2012 Jul 20. PMID: 22821993. [PubMed]
    • Laughner JI, Zhang S, Li H, Shao CC, Efimov IR. Mapping cardiac surface mechanics with structured light imaging. Am J Physiol Heart Circ Physiol. 2012 Sep 15;303(6):H712-20. Epub 2012 Jul 13. PMID: 22796539. [PubMed]
    • Ambrosi CM, Fedorov VV, Schuessler RB, Rollins AM, Efimov IR. Quantification of Fiber Orientation in the Canine Atrial Pacemaker Complex using Optical Coherence Tomography. J Biomed Opt. 2012 Jul;17(7):071309. PMID: 22894470. [PubMed]
    • Efimov IR, Gutbrod S. "Fibrillating atrium: rabbit warren! Not beehive!". J Cardiovasc Electrophysiol. 2013 Mar;24(3):336-7. doi: 10.1111/jce.12044. Epub 2012 Dec 4. PMID: 23210845. [PubMed]
    • Rantner LJ, Arevalo HJ, Constantino JL, Efimov IR, Plank G, Trayanova NA. Three-Dimensional Mechanisms of Increased Vulnerability to Electric Shocks in Myocardial Infarction: Altered Virtual Electrode Polarizations and Conduction Delay in the Peri-Infarct Zone. J Physiol. 2012 Sep 15;590(Pt 18):4537-51. doi: 10.1113/jphysiol.2012.229088. Epub 2012 May 14. PMID: 22586222. [PubMed]
    • Lou Q, Janardhan A, Efimov IR. Remodeling of calcium handling in human heart failure. Adv Exp Med Biol. 2012;740:1145-74. doi: 10.1007/978-94-007-2888-2_52. PMID: 22453987. [PubMed]
    • Janardhan AH, Li W, Fedorov VV, Yeung M, Wallendorf MJ, Schuessler RB, Efimov IR. A novel low-energy electrotherapy that terminates ventricular tachycardia with lower energy than a biphasic shock when antitachycardia pacing fails. J Am Coll Cardiol. 2012 Dec 11;60(23):2393-8. doi: 10.1016/j.jacc.2012.08.1001. Epub 2012 Nov 7. PMID: 23141483. [PubMed]
    • Glukhov AV, Fedorov VV, Kalish PW, Ravikumar VK, Lou Q, Janks D, Schuessler RB, Moazami N, Efimov IR. Conduction remodeling in human end-stage nonischemic left ventricular cardiomyopathy. Circulation. 2012 Apr 17;125(15):1835-47. doi: 10.1161/CIRCULATIONAHA.111.047274. Epub 2012 Mar 12. PMID: 22412072. [PubMed]
    • Laughner JI, Sulkin MS, Wu Z, Deng CX, Efimov IR. Three Potential Mechanisms for Failure of HIFU Ablation in Cardiac Tissue. Circ Arrhythm Electrophysiol. 2012 Apr;5(2):409-16. doi: 10.1161/CIRCEP.111.967216. Epub 2012 Feb 9. PMID: 22322367. [PubMed]
    • Nikolaidou T, Aslanidi OV, Zhang H, Efimov IR. Structure-Function Relationship in the Sinus and Atrioventricular Nodes. Pediatr Cardiol. 2012 Aug;33(6):890-9. doi: 10.1007/s00246-012-0249-0. Epub 2012 Mar 3. PMID: 22391764. [PubMed]
    • Lou Q, Janks DL, Holzem K, Lang D, Onal B, Ambrosi CM, Fedorov VV, Wang IW, Efimov IR. Right Ventricular Arrhythmogenesis in Failing Human Heart: The Role of Conduction and Repolarization Remodeling. Am J Physiol Heart Circ Physiol. 2012 Dec 15;303(12):H1426-34. doi: 10.1152/ajpheart.00457.2012. Epub 2012 Oct 5. PMID: 23042951. [PubMed]
    • Wang YT, Popović ZB, Efimov IR, Cheng Y. Longitudinal Study of Cardiac Remodelling in Rabbits Following Infarction. Can J Cardiol. 2012 Mar-Apr;28(2):230-8. doi: 10.1016/j.cjca.2011.11.003. Epub 2012 Jan 21. PMID: 22265993. [PubMed]
    • Wang YT, Efimov IR, Cheng Y. Electroporation Induced by Internal Defibrillation Shock with and without Recovery in Intact Rabbit Hearts. Am J Physiol Heart Circ Physiol. 2012 Aug 15;303(4):H439-49. doi: 10.1152/ajpheart.01121.2011. Epub 2012 Jun 22. PMID: 22730387. [PubMed]
    • Pietka TA, Sulkin MS, Kuda O, Wang W, Zhou D, Yamada KA, Yang K, Su X, Gross RW, Nerbonne JM, Efimov IR, Abumrad NA. CD36 protein influences myocardial Ca2+ homeostasis and phospholipid metabolism: conduction anomalies in CD36-deficient mice during fasting. J Biol Chem. 2012 Nov 9;287(46):38901-12. doi: 10.1074/jbc.M112.413609. Epub 2012 Sep 27. PMID: 23019328. [PubMed]
    • Lou Q, Li W, Efimov IR. The role of dynamic instability and wavelength in arrhythmia maintenance as revealed by panoramic imaging with blebbistatin vs. 2,3-butanedione monoxime. Am J Physiol Heart Circ Physiol. 2012 Jan;302(1):H262-9. Epub 2011 Oct 28. PMID: 22037192. [PubMed]
    • Holzem KM, Efimov IR. Arrhythmogenic remodelling of activation and repolarization in the failing human heart. Europace 2012 Nov;14 Suppl 5:v50-v57. doi: 10.1093/europace/eus275. PMID: 23104915. [PubMed]
    • Egorov YV, Glukhov AV, Efimov IR, Rosenshtraukh LV. Hypothermia-induced spatially discordant action potential duration alternans and arrhythmogenesis in non-hibernating versus hibernating mammals. Am J Physiol Heart Circ Physiol. 2012 Oct 15;303(8):H1035-46. doi: 10.1152/ajpheart.00786.2011. Epub 2012 Aug 10. PMID: 22886418. [PubMed]
    • Janardhan AH, Li W, Fedorov VV, Yeung M, Wallendorf MJ, Schuessler RB, Efimov IR. A novel low-energy electrotherapy that terminates ventricular tachycardia with lower energy than a biphasic shock when antitachycardia pacing fails. J Am Coll Cardiol. 2012 Dec 11;60(23):2393-8. doi: 10.1016/j.jacc.2012.08.1001. Epub 2012 Nov 7. PMID: 23141483. [PubMed]
    • Smith AW, Segar CE, Nguyen PK, MacEwan MR, Efimov IR, Elbert DL. Long-term culture of HL-1 cardiomyocytes in modular poly(ethylene glycol) microsphere-based scaffolds crosslinked in the phase-separated state. Acta Biomater. 2012 Jan;8(1):31-40. doi: 10.1016/j.actbio.2011.08.021. Epub 2011 Aug 30. PMID: 21920469. [PubMed]

    2011

    • Fedorov VV, Ambrosi CM, Kostecki G, Hucker WJ, Glukhov AV, Wuskell J, Loew LM, Moazami N, Efimov IR. Anatomic localization and autonomic modulation of atrioventricular junctional rhythm in failing human hearts. Circ Arrhythm Electrophysiol. 2011 Aug;4(4):515-25. Epub 2011 Jun 6. PMID: 21646375. [PubMed]
    • Swaminathan PD, Purohit A, Soni S, Voigt N, Singh MV, Glukhov AV, Gao Z, He JB, Luczak ED, Joiner MA, Kutschke W, Yang J, Donahue JK, Weiss RM, Grumbach IM, Ogawa M, Chen PS, Efimov IR, Dobrev D, Mohler PJ, Hund TJ, Anderson ME. Oxidized CaMKII causes cardiac sinus node dysfunction in mice. J Clin Invest. 2011 Aug;121(8):3277-88. Epub 2011 Jul 25. PMID: 21785215. [PubMed]
    • Bordas R, Gillow K, Lou Q, Efimov IR, Gavaghan D, Kohl P, Grau V, Rodriguez B. Full Rabbit-Specific Ventricular Model of Cardiac Electrophysiological Function including Specialized Conduction System. Prog Biophys Mol Biol. 2011 Oct;107(1):90-100. doi: 10.1016/j.pbiomolbio.2011.05.002. Epub 2011 Jun 13. PMID: 21672547. [PubMed]
    • Lang D, Glukhov AV, Efimova T, Efimov IR. The role of Pyk2 in cardiac arrhythmogenesis. Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H975-83. doi: 10.1152/ajpheart.00241.2011. Epub 2011 Jun 10. PMID: 21666110. [PubMed]
    • Quinn TA, Granite S, Allessie MA, Antzelevitch C, Bollensdorff C, Bub G, Burton RAB, Cerbai E, Chen PS, Delmar M, DiFrancesco D, Earm YE, Efimov IR, Egger M, Entcheva E, Fink M, Fischmeister R, Franz MR, Garny A, Giles WR, Hannes T, Harding SE, Hunter PJ, Iribe G, Jalife J, Johnson CR, Kass RS, Kodama I, Koren G, Lord P, Markhasin VS, Matsuoka S, McCulloch AD, Mirams GR, Morley GE, Nattel S, Noble D, Olesen SP, Panfilov AV, Trayanova NA, Ravens U, Richard S, Rosenbaum DS, Rudy Y, Sachs F, Sachse FB, Saint DA, Schotten U, Solovyova O, Taggart P, Tung L, Varró A, Volders PG, Wang K, Weiss JN, White E, Wilders R, Winslow RL, Kohl P. Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): Standardised Reporting for Model Reproducibility, Interoperability, and Data Sharing. Prog Biophys Mol Biol. 2011 Oct;107(1):4-10. doi: 10.1016/j.pbiomolbio.2011.07.001. Epub 2011 Jul 6. PMID: 21745496. [PubMed]
    • Ambrosi CM, Ripplinger CM, Efimov IR, Fedorov VV. Termination of sustained atrial flutter and fibrillation using low energy multiple shock therapy. Heart Rhythm. 2011 Jan;8(1):101-8. doi: 10.1016/j.hrthm.2010.10.018. Epub 2010 Oct 19. PMID: 20969974. [PubMed]
    • Greener ID, Monfredi O, Inada S, Chandler NJ, Tellez JO, Atkinson A, Taube MA, Billeter R, Anderson RH, Efimov IR, Molenaar P, Sigg DC, Sharma V, Boyett MR, Dobrzynski H. Molecular architecture of the human specialised atrioventricular conduction axis. J Mol Cell Cardiol. 2011 Apr;50(4):642-51. doi: 10.1016/j.yjmcc.2010.12.017. Epub 2011 Jan 21. PMID: 21256850. [PubMed]
    • Lou Q, Fedorov VV, Glukhov AV, Fast VG, Moazami N, Efimov IR. Transmural heterogeneity and remodeling of ventricular excitation-contraction coupling in human heart failure. Circulation. 2011 May 3;123(17):1881-90. doi: 10.1161/CIRCULATIONAHA.110.989707. Epub 2011 Apr 18. PMID: 21502574. [PubMed]
    • Fedorov VV, Glukhov AV, Ambrosi CM, Kostecki G, Chang R, Janks D, Schuessler RB, Moazami N, Nichols CG, Efimov IR. Effects of KATP channel openers diazoxide and pinacidil in coronary-perfused atria and ventricles from failing and non-failing human hearts. J Mol Cell Cardiol. 2011 Aug;51(2):215-25. doi: 10.1016/j.yjmcc.2011.04.016. Epub 2011 May 7. PMID: 21586291. [PubMed]
    • Li W, Janardhan AH, Fedorov VV, Sha Q, Schuessler RB, Efimov IR. Low-energy multistage atrial defibrillation therapy terminates atrial fibrillation with less energy than a single shock. Circ Arrhythm Electrophysiol. 2011 Dec;4(6):917-25. Epub 2011 Oct 6. PMID: 21980076. [PubMed]
    • Lou Q, Li W, Efimov IR. Multiparametric Optical Mapping of the Langendorff-perfused Rabbit Heart. J Vis Exp. 2011 Sep 13;(55). pii: 3160. doi: 10.3791/3160. PMID: 21946767. [PubMed]
    • Lang D, Petrov V, Lou Q, Osipov G, Efimov IR. Spatiotemporal control of heart rate in a rabbit heart. J Electrocardiol. 2011 Nov-Dec;44(6):626-34. doi: 10.1016/j.jelectrocard.2011.08.010. Epub 2011 Sep 19. PMID: 21937057. [PubMed]
    • Lang D, Sulkin M, Lou Q, Efimov IR. Optical Mapping of Action Potentials and Calcium Transients in the Mouse Heart. J Vis Exp. 2011 Sep 13;(55). pii: 3275. doi: 10.3791/3275. PMID: 21946907. [PubMed]

    2010

    • Fedorov VV, Glukhov AV, Chang R, Kostecki G, Aferol1 H, Hucker WJ, Wuskell J, Loew LM, Schuessler RB; Moazami N, Efimov IR. Optical mapping of the isolated coronary-perfused human sinus node. J Am Coll Cardiol. 2010 Oct 19;56(17):1386-94. doi: 10.1016/j.jacc.2010.03.098. PMID: 20946995. [PubMed]
    • Efimov IR, Fedorov VV, Glukhov A, Lou Q, Ambrosi C, Janks D, Hucker WJ, Kurian T, Schuessler RB, Moazami N. Multiscale imaging of the human heart: Building the foundation for human systems physiology and translational medicine. Conf Proc IEEE Eng Med Biol Soc. 2010;2010:5177-80. doi: 10.1109/IEMBS.2010.5626151. PMID: 21095821. [PubMed]
    • Fedorov VV, Chang R, Glukhov AV, Kostecki G, Janks D, Schuessler RB, Efimov IR. Complex interactions between the sinoatrial node and atrium during reentrant arrhythmias in the canine heart. Circulation. 2010 Aug 24;122(8):782-9. doi: 10.1161/CIRCULATIONAHA.109.935288. Epub 2010 Aug 9. PMID: 20697021. [PubMed] [PDF]
    • Laughner JI, Gong Y, Filas BA, Zhang S, Efimov IR. Structured light imaging of epicardial mechanics. Conf Proc IEEE Eng Med Biol Soc. 2010;2010:5157-60. doi: 10.1109/IEMBS.2010.5626117. PMID: 21095816. [PubMed]
    • Glukhov AV, Fedorov VV, Lou Q, Ravikumar VK, Kalish PW, Schuessler RB, Moazami N, Efimov IR. Transmural Dispersion Of Repolarization In Failing And Non Failing Human Ventricle. Circ Res. 2010 Mar 19;106(5):981-91. doi: 10.1161/CIRCRESAHA.109.204891. Epub 2010 Jan 21. PMID: 20093630. [PubMed]
    • Kurian T, Ambrosi C, Hucker W, Fedorov VV, Efimov IR. Anatomy and Electrophysiology of the Human AV Node. Pacing Clin Electrophysiol. 2010 Jun 1;33(6):754-62. doi: 10.1111/j.1540-8159.2010.02699.x. Epub 2010 Feb 18. PMID: 20180918. [PubMed]
    • Gronich N, Kumar A, Zhang Y, Efimov IR, Soldatov NM. Molecular remodeling of ion channels, exchangers and pumps in atrial and ventricular myocytes in ischemic cardiomyopathy. Channels (Austin). 2010 Mar-Apr;4(2):101-7. Epub 2010 Mar 18. PMID: 20090424. [PubMed] [PDF]
    • Glukhov AV, Fedorov VV, Anderson ME, Mohler PJ, Efimov IR. Functional Anatomy Of The Murine Sinus Node: High-Resolution Optical Mapping Of Ankyrin-B Heterozygous Mice. Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H482-91. doi: 10.1152/ajpheart.00756.2009. Epub 2010 Jun 4. PMID: 20525877. [PubMed]
    • Glukhov AV, Flagg TP, Fedorov VV, Efimov IR, Nichols CG. Differential KATP channel pharmacology in intact mouse heart. J Mol Cell Cardiol. 2010 Jan;48(1):152-60. doi: 10.1016/j.yjmcc.2009.08.026. Epub 2009 Sep 8. PMID: 19744493. [PubMed]
    • Efimov IR, Fedorov VV, Joung B, Lin SF. Mapping Cardiac Pacemaker Circuits: Methodological Puzzles of the Sino-Atrial Node Optical Mapping. Circ Res. 2010 Feb 5;106(2):255-71. doi: 10.1161/CIRCRESAHA.109.209841. PMID: 20133911. [PubMed] [PDF]
    • Kurian TK, Efimov IR. Mechanisms of fibrillation: neurogenic or myogenic? Reentrant or focal? Multiple or single? Still puzzling after 160 years of inquiry. J Cardiovasc Electrophysiol. 2010 Nov;21(11):1274-5. doi: 10.1111/j.1540-8167.2010.01820.x. PMID: 20550608. [PubMed] [PDF]

    2009

    • Mowrey KA, Efimov IR, Cheng Y. Membrane time constant during internal defibrillation strength shocks in intact heart: Effects of Na+ and Ca2+ channel blockers. J Cardiovasc Electrophysiol. 2009 Jan;20(1):85-92. doi: 10.1111/j.1540-8167.2008.01273.x. Epub 2008 Sep 3. PMID: 18775052. [PubMed] [PDF]
    • Ripplinger CM, Lou Q, Li W, Hadley J, Efimov IR. Panoramic Imaging Reveals Basic Mechanisms Of Induction and Termination of Ventricular Tachycardia in Rabbit Heart with Chronic Infarction: Implications for Low Voltage Cardioversion. Heart Rhythm. 2009 Jan;6(1):87-97. doi: 10.1016/j.hrthm.2008.09.019. Epub 2008 Sep 23. PMID: 18996057. [PubMed]
    • Cakulev I, Efimov IR, Waldo AL. Cardioversion: History, Present and Future. Circulation. 2009 Oct 20;120(16):1623-32. doi: 10.1161/CIRCULATIONAHA.109.865535. PMID: 19841308. [PubMed] [PDF]
    • Li W, Ripplinger CM, Lou Q, Efimov IR. Multiple Monophasic Shocks Improve Electrotherapy of Ventricular Tachycardia in a Rabbit Model of Chronic Infarction. Heart Rhythm. 2009 Jul;6(7):1020-7. doi: 10.1016/j.hrthm.2009.03.015. Epub 2009 Mar 11. PMID: 19560090. [PubMed]
    • Ambrosi CM, Moazami N, Rollins AM, Efimov IR. Virtual Histology of the Human Heart Using Optical Coherence Tomography. J Biomed Opt. 2009 Sep-Oct;14(5):054002. doi: 10.1117/1.3213604. PMID: 19895104. [PubMed] [PDF]
    • Fedorov VV, Schuessler RB, Hemphill M, Ambrosi CM, Chang R, Voloshina AS, Brown K, Hucker WJ, Efimov IR. Structural and Functional Evidence for Discrete Exit Pathways that Connect the Canine Sino-Atrial Node and Atria. Circ Res. 2009 Apr 10;104(7):915-23. doi: 10.1161/CIRCRESAHA.108.193193. Epub 2009 Feb 26. PMID: 19246679. [PubMed] [PDF]
    • Tereshchenko LG, Faddis MN, Fetics BJ, Zelik KE, Efimov IR, Berger RD. Transient Local Injury Current in Right Ventricular Electrogram after ICD Shock Predicts Heart Failure Progression. J Am Coll Cardiol. 2009 Aug 25;54(9):822-8. doi: 10.1016/j.jacc.2009.06.004. PMID: 19695461. [PubMed] [PDF]
    • Efimov IR. Naum Lazarevich Gurvich (1905-1981) and his contribution to the history of defibrillation. Cardiol J. 2009;16(2):190-3. PMID: 19387971. [PubMed] [PDF]
    • Egorov IuV, Glukhov AV, Artiukhov VS, Efimov IR, Rozenshtraukh LV. Comparative study of cardiac alternans of action potential duration in hypothermia in rabbits and ground squirrels. Ross Fiziol Zh Im I M Sechenova. 2009 May;95(5):532-42. Russian. PMID: 19569529. [PubMed]
    • Lombardi R, Rodriguez G, Chen SN, Ripplinger CM, Li W, Chen J, Willerson JT, Betocchi S, Wickline SA, Efimov IR, Marian AJ. Resolution of Established Cardiac Hypertrophy and Fibrosis and Preventions of Heart Failure in a Transgenic Rabbit Model of Human Cardiomyopathy Through Thiol-sensitive Mechanisms. Circulation. 2009 Mar 17;119(10):1398-407. doi: 10.1161/CIRCULATIONAHA.108.790501. Epub 2009 Mar 2. PMID: 19255346. [PubMed]
    • Efimov IR. Chronaxie of Defibrillation: A pathway toward further optimization of defibrillation waveform? J Cardiovasc Electrophysiol. 2009 Mar;20(3):315-7. doi: 10.1111/j.1540-8167.2008.01330.x. Epub 2008 Oct 14. PMID: 19175836. [PubMed] [PDF]

    2008

    • Efimov IR. Nature Versus Nurture in Cardiac Conduction: Toward Integrative Paradigm of Cardiac Tissue Engineering. Circ Res. 2008 Jul 18;103(2):119-21. doi: 10.1161/CIRCRESAHA.108.180828. PMID: 18635826. [PubMed] [PDF]
    • Lou Q, Ripplinger CM, Bayly PV, Efimov IR. Quantitative Panoramic Imaging of Epicardial Electrical Activity. Ann Biomed Eng. 2008 Oct;36(10):1649-58. doi: 10.1007/s10439-008-9539-3. Epub 2008 Jul 25. PMID: 18654852. [PubMed]
    • Hucker WJ, McCain ML, Laughner JI, Iaizzo PA, Efimov IR. Connexin 43 Expression Delineates Two Discrete Pathways in the Human Atrioventricular Junction. Anat Rec (Hoboken). 2008 Feb;291(2):204-15. PMID: 18085635. [PubMed] [PDF]
    • Fedorov VV, Nikolski VP, Efimov IR. Effect of electroporation on cardiac electrophysiology. Methods Mol Biol. 2008;423:433-48. doi: 10.1007/978-1-59745-194-9_34. PMID: 18370220. [PubMed] [PDF]
    • Fedorov VV, Glukhov AV, Sudharshan S, Egorov Y, Rosenshtraukh LV, Efimov IR. Electrophysiological mechanisms of antiarrhythmic protection during hypothermia in winter hibernating versus nonhibernating mammals. Heart Rhythm. 2008 Nov;5(11):1587-96. doi: 10.1016/j.hrthm.2008.08.030. Epub 2008 Aug 31. PMID: 18984537. [PubMed]
    • Hucker WJ, Fedorov VV, Foyil KV, Moazami N, Efimov IR. Optical Mapping of the Human Atrioventricular Junction. Circulation. 2008 Mar 18;117(11):1474-7. doi: 10.1161/CIRCULATIONAHA.107.733147. PMID: 18347223. [PubMed] [PDF]
    • Fleming C, Ripplinger CM, Webb B, Efimov IR, Rollins AM. Quantification of Cardiac Fiber Orientation Using Optical Coherence Tomography. J Biomed Opt. 2008 May-Jun;13(3):030505. doi: 10.1117/1.2937470. PMID: 18601522. [PubMed] [PDF]
    • Glukhov AV, Egorov IuV, Efimov IR, Rozenshtraukh LV. Spatiotemporal characteristics of activation of the heart of hibernating and non-hibernating mammals during hypothermia. Kardiologiia. 2008;48(12):34-41. Russian. PMID: 19076092. [PubMed]
    • Fedorov VV, Kostecki G, Hemphill M, Efimov IR. Atria are more susceptible to electroporation than ventricles: Implications for atrial stunning, shock-induced arrhythmia and defibrillation failure.Heart Rhythm. 2008 Apr;5(4):593-604. doi: 10.1016/j.hrthm.2008.01.026. Epub 2008 Jan 29. PMID: 18362029. [PubMed] [PDF]
    • Kim SC, Vasanji A, Efimov IR, Cheng Y. Spatial Distribution and Extent of Electroporation by Strong Internal Shock in Intact Structurally Normal and Chronically Infarcted Rabbit Hearts. J Cardiovasc Electrophysiol. 2008 Oct;19(10):1080-9. doi: 10.1111/j.1540-8167.2008.01201.x. Epub 2008 May 9. PMID: 18479336. [PubMed]
    • Varma N, Efimov IR. Right pectoral implantable cardioverter defibrillators: role of the proximal (SVC) coil. Pacing Clin Electrophysiol. 2008 Aug;31(8):1025-35. doi: 10.1111/j.1540-8159.2008.01130.x. PMID: 18684259. [PubMed] [PDF]
    • Hucker WJ, Ripplinger CM, Fleming CP, Fedorov VV, Rollins AM, Efimov IR. Bimodal Biophotonic Imaging of the Structure-Function: Relationship in Cardiac Tissue. J Biomed Opt. 2008 Sep-Oct;13(5):054012. doi: 10.1117/1.2975826. PMID: 19021392. [PubMed] [PDF]
    • Li J, Greener ID, Inada S, Nikolski VP, Yamamoto M, Billeter R, Efimov IR, Dobrzynski H, Boyett MR. Computer three-dimensional reconstruction of the atrioventricular node. Circ Res. 2008 Apr 25;102(8):975-85. doi: 10.1161/CIRCRESAHA.108.172403. Epub 2008 Feb 28. PMID: 18309098. [PubMed] [PDF]

    2007

    • Bishop MJ, Rodriguez B, Qu F, Efimov IR, Gavaghan DJ, Trayanova NA. Synthesis Of Optical Recordings During Arrhythmia And Defibrillation: An Inquiry Into The Role Of Photon Scattering In Signal Distortion. Biophys. J., 2007, 93(10): 3714-26. PMID: 17978166. [PubMed] [PDF]
    • Sharma V, Qu F, Nikolski VP, DeGroot P, Efimov IR. Direct Measurements of Membrane Time Constant During Defibrillation Strength Shocks. Heart Rhythm. 2007 Apr;4(4):478-86. Epub 2006 Dec 15. PMID: 17399638. [PubMed] [PDF]
    • Ripplinger CM, Li W, Hadley J, Chen J, Rothenberg F, Lombardi R, Wickline SA, Marian AJ, Efimov IR. Enhanced transmural fiber rotation and Cx43 heterogeneity are associated with an increased upper limit of vulnerability in a transgenic rabbit model of human hypertrophic cardiomyopathy, Circulation Research, 2007, 101(10): 1049-57. PMID: 17399638. [PubMed] [PDF]
    • Fedorov VV, Lozinsky IT, Sosunov EA, Anyukhovsky EP, Rosen MR, Balke WC, Efimov IR. Application of blebbistatin as an excitation-contraction uncoupler for electrophysiological study of rat and rabbit hearts. Heart Rhythm. 2007 May;4(5):619-26. Epub 2007 Jan 7. PMID: 17467631. [PubMed] [PDF Federov] [PDF Li and Nattel]
    • Efimov IR. Innovation in optical imaging: looking inside the heart. Heart Rhythm. 2007 Jul;4(7):925-6. Epub 2007 Apr 25. Editorial. PMID: 17599679. [PubMed] [PDF]
    • Ryu K, Li L, Khrestian C, Matsumoto N, Sahadevan J, Ruehr M, Van Wagoner D, Efimov IR, Waldo, A. Effects of Sterile Pericarditis on Connexins 40 and 43 in the Atria: Correlation with Abnormal Conduction and Atrial Arrhythmias. Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H1231-41. Epub 2007 Apr 13. PMID: 17434983. [PubMed] [PDF]
    • Van Der Heyden MAG, Kok B, Kouwenhoven EN, Toien O, Barnes BM, Fedorov VG, Efimov IR, Opthof T. Cloning, sequence analysis and phylogeny of Connexin43 isolated from American black bear heart. DNA Seq. 2007 Oct;18(5):380-4. PMID: 17654014. [PubMed] [PDF]
    • Qu F, Ripplinger CM, Nikolski VP, Grimm C, Efimov IR. Three Dimensional Panoramic Imaging of Cardiac Arrhythmias in the Rabbit Heart. J. Biomed. Opt. 2007, 12(4): 044019. PMID: 17867823. [PubMed] [PDF]
    • Hucker WJ, Sharma V, Nikolski VP, Efimov IR. Atrio-Ventricular Conduction with and without AV Nodal Delay: Two Pathways to the Bundle of His in the Rabbit Heart. Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H1122-30. Epub 2007 May 11. PMID: 17496219. [PubMed] [PDF]
    • Hucker WJ, Nikolski VP, Efimov IR. Autonomic Control and Innervation of the AV Junctional Pacemaker. Heart Rhythm. 2007 Oct;4(10):1326-35. Epub 2007 Jun 16. PMID: 17905339. [PubMed] [PDF]
    • Filas BA, Efimov IR, Taber LA. Optical Coherence Tomography as a Tool for Measuring Morphogenetic Deformation of the Looping Heart. Anat Rec (Hoboken). 2007 Sep;290(9):1057-68. PMID: 17721979. [PubMed] [PDF]
    • Efimov IR. How to fix a broken heart: Modern Bioengineering Approaches to Cardiovascular Diseases, from Molecules to Patients, Club Bilingua, Moscow, Russia, September 12, 2007.
    • Glukhov AV, Egorov IuV, Fedorov VV, Efimov IR, Rozenshtraukh LV. The effect of hypothermia on the wavelength and vulnarability to ventricular arrhythmias in mammals. Ross Fiziol Zh Im I M Sechenova. 2007 Mar;93(3):289-99. Russian. PMID: 17598472. [PubMed] [PDF]

    2006

    • Kroll MW, Efimov IR, Tchou PJ. Present understanding of shock polarity for internal defibrillation: the obvious and non-obvious clinical implications. Pacing Clin Electrophysiol. 2006 Aug;29(8):885-91.PMID: 16923006. [PubMed]
    • Efimov IR. Low Voltage Defibrillation, Kavli Institute for Theoretical Physics, Santa Barbara, CA, July 27, 2006. [PDF]
    • Efimov IR, Ripplinger CM. Tornado in a dish: revealing the mechanisms of ventricular arrhythmias in engineered cardiac tissues. Cardiovasc Res. 2006 Feb 1;69(2):307-8. Epub 2005 Dec 1. Editorial. PMID: 16325163. [PubMed] [PDF]
    • Fedorov VV, Hucker WJ, Dobrzynski H, Efimov IR. Postganglionic nerve stimulation induces temporal inhibition of excitability in rabbit sinoatrial node. Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H612-23. Epub 2006 Mar 24. PMID: 16565321. [PubMed] [PDF]
    • Boyett MR, Inada S, Yoo S, Li J, Liu J, Tellez J, Greener ID, Honjo H, Billeter R, Lei M, Zhang H, Efimov IR, Dobrzynski H. Connexins in the sinoatrial and atrioventricular nodes. Adv Cardiol. 2006; 42:175-97. PMID: 16646591. [PubMed] [PDF]
    • Efimov IR, Ripplinger CM. Virtual electrode hypothesis of defibrillation. Heart Rhythm. 2006 Sep;3(9):1100-2. Epub 2006 Mar 10. PMID: 16945810. [PubMed] [PDF]
    • Efimov IR, Fedorov VV. Precordial thump and commotio cordis: The yin and yang of mechanoelectric feedback in the heart. Heart Rhythm, 2006, 3(2): 187-8. Editorial. PMID: 16443534. [PubMed] [PDF]
    • Nikolskaya AV, Nikolski VP, Efimov IR. Gene printer: laser-scanning targeted transfection of cultured cardiac neonatal rat cells. Cell Commun Adhes. 2006 Jul-Aug; 13(4):217-22. PMID: 16916749. [PubMed] [PDF]
    • Jenkins MW, Rothenberg F, Roy D, Nikolski VP, Watanabe M, Wilson DL, Efimov IR, Rollins AM. Embryonic Cardiography using Gated Optical Coherence Tomography. Opt Express. 2006 Jan 23;14(2):736-48. PMID: 19503392. [PubMed] [PDF]
    • Yoo S, Dobrzynski H, Fedorov VV, Xu SZ, Yamanushi TT, Jones SA, Yamamoto M, Nikolski VP, Efimov IR, Boyett MR. Localization of Na+ Channel Isoforms at the Atrioventricular Junction and Atrioventricular Node in the Rat. Circulation. 2006 Sep 26;114(13):1360-71. Epub 2006 Sep 11. PMID: 16966585. [PubMed]
    • Rothenberg F, Efimov IR. Three-Dimensional Anatomy of the Conduction System of the Early Embryonic Rabbit Heart. Anat Rec A Discov Mol Cell Evol Biol. 2006 Jan;288(1):3-7. PMID: 16287158. [PubMed] [PDF]
    • Ripplinger CM, Krinsky VI, Nikolski VP, Efimov IR. Mechanisms of unpinning and termination of ventricular tachycardia: Implications for low voltage defibrillation. Am J Physiol Heart Circ Physiol. 2006 Jul;291(1):H184-92. Epub 2006 Feb 24. PMID: 16501014. [PubMed] [PDF]
    • Efimov IR. Reentrant Arrhythmias, Mathematical Biosciences Institute, Columbus, OH. September 28, 2006.

    2005

    • Jenkins M, Wade RS, Cheng Y, Rollins AM, Efimov IR. Optical coherence tomography imaging of the Purkinje network. J Cardiovasc Electrophysiol. 2005 May;16(5):559-60. PMID: 15877631. [PubMed]
    • Nikolski VP, Efimov IR Electroporation of the heart. Europace. 2005 Sep;7 Suppl 2:146-54. PMID: 16102512. [PubMed] [PDF]
    • Li L, Nikolski V, Wallick DW, Efimov IR, Cheng Y. Mechanisms of enhanced shock-induced arrhythmogenesis in the rabbit heart with healed myocardial infarction. Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1054-68. Epub 2005 May 6. PMID: 15879480. [PubMed] [PDF]
    • Efimov IR. Imaging Arrhythmias: Toward Painless Defibrillation. Cardiac Bioelectricity and Arrhythmia Center, Washington University, St. Louis, MO, October 17, 2005.
    • Hucker WJ, Nikolski VP, Efimov IR. Optical mapping of the atrioventricular junction. J Electrocardiol. 2005 Oct;38(4 Suppl):121-5. Review. PMID: 16226086. [PubMed] [PDF]
    • Efimov IR, Fedorov VV. Chessboard of atrial fibrillation: Reentry or focus? Single or multiple source(s)? Neurogenic or myogenic? Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H977-9. Editorial comment. PMID: 16100254. [PubMed]
    • Qu F, Li L, Nikolski V, Sharma V, Efimov IR. Mechanisms of Superiority of Ascending Ramp Waveforms: New Insights into Mechanisms of Shock-induced Vulnerability and Defibrillation. Am J Physiol Heart Circ Physiol. 2005 Aug;289(2):H569-77. Epub 2005 Mar 25. PMID: 15792989. [PubMed] [PDF]
    • Fedorov VV, Li L, Glukhov A, Shishkina I, Aliev RP, Mikheeva T, Nikolski VP, Rosenshtraukh LV, Efimov IR. Hibernator Citellus undulatus maintains safe cardiac conduction and is protected against tachyarrhythmias during extreme hypothermia: possible role of Cx43 and Cx45 upregulation. Heart Rhythm. 2005 Sep;2(9):966-75. PMID: 16171752. [PubMed] [PDF] [Cover]
    • Deng, CX, Qu F, Nikolski VP, Zhou Y, Efimov IR. Fluorescent real-time monitoring of cardiac high-intensity focused ultrasound ablation. Ann. Biomed. Eng, 2005, 33(10): 1417-1424. [PDF]
    • Qu F, Zarubin F, Wollenzier B, Nikolski VP, Efimov IR. The Gurvich waveform has lower defibrillation threshold than the rectilinear waveform and the truncated exponential waveform in the rabbit heart. Can J Physiol Pharmacol. 2005 Feb;83(2):152-60. PMID: 15791288. [PubMed]
    • Rodriguez B, Li L, Eason JC, Efimov IR, Trayanova NA. Differences Between Left and Right Ventricular Chamber Geometry Affect Cardiac Vulnerability to Electric Shocks. Circ Res. 2005 Jul 22;97(2):168-75. Epub 2005 Jun 23. PMID: 15976315. [PubMed] [PDF] [Cover]
    • Dobrzynski H, Li J, Tellez J, Greener ID, Nikolski VP, Wright SE, Parson SH, Jones SA, Lancaster MK, Yamamoto M, Honjo H, Takagishi Y, Kodama I, Efimov IR, Billeter R, Boyett MR. Computer three-dimensional reconstruction of the sinoatrial node. Circulation. 2005 Feb 22;111(7):846-54. Epub 2005 Feb 7. PMID: 15699261. [PubMed] [PDF]
    • Rothenberg F, Nikolski VP, Watanabe M, Efimov IR. Electrophysiology and anatomy of embryonic rabbit hearts before and after septation. Am J Physiol Heart Circ Physiol. 2005 Jan;288(1):H344-51. Epub 2004 Aug 26. PMID: 15331361. [PubMed] [Cover]
    • Rozenshtraukh LV, Fedorov VV, Aliev RR, Glukhov AV, Mikheeva TV, Reznik AV, Efimov IR. [Pattern of Excitation in Isolated Heart of Hibernator Ground Squirrel Citellus undulatus]. Kardiologiia. 2005;45(4):4-10. PMID: 15940184. [PubMed]

    2004

    • Cheng Y, Li L, Nikolski V, Wallick DW, Efimov IR. Shock-induced arrhythmogenesis is enhanced by 2,3-butanedione monoxime compared with cytochalasin D.Am J Physiol Heart Circ Physiol. 2004; 286(1): H310-8. Epub 2003 Sep 04. PMID: 12958029. [PubMed]
    • Efimov IR, Nikolski VP, Rothenberg F, Greener ID, Li J, Dobrzynski H, Boyett M. Structure-function relationship in the AV junction. Anat Rec A Discov Mol Cell Evol Biol. 2004 Oct;280(2):952-65. PMID: 15368340. [PubMed] [PDF]
    • Efimov IR. Cardiac pacing and defibrillation: history and mechanisms of antiarrhythmia therapy, Washington University, MO, September 17, 2004.
    • Nikolski VP, Sambelashvili AT, Krinsky VI, Efimov IR. Effects of electroporation on optically recorded transmembrane potential responses to high-intensity electrical shocks. Am J Physiol Heart Circ Physiol. 2004 Jan;286(1):H412-8. Epub 2003 Oct 2. PMID: 14527941. [PubMed] [PDF]
    • Efimov IR. Cardiac conduction and resistance to ventricular fibrillation in Siberian hibernator Cittelus undulatus: Does the switch from Cx43 to Cx45 improve safety of slow conduction? Life in Cold, Alaska, July 31, 2004. [PDF]
    • Pazo D, Kramer L, Pumir A, Kanani S, Efimov I, Krinsky V. Pinning force in active media. Phys Rev Lett. 2004 Oct 15;93(16):168303. Epub 2004 Oct 15. PMID: 15525042. [PubMed] [PDF]
    • Rothenberg F, Efimov IR, Watanabe M. Functional imaging of the embryonic pacemaking and cardiac conduction system over the past 150 years: technologies to overcome the challenges. Anat Rec A Discov Mol Cell Evol Biol. 2004 Oct;280(2):980-9. PMID: 15372434. [PubMed] [PDF]
    • Sambelashvili A, Efimov IR. Dynamics of virtual electrode-induced scroll-wave reentry in a 3D bidomain model. Am J Physiol Heart Circ Physiol. 2004 Oct;287(4):H1570-81. PMID: 15371264. [PubMed] [PDF]
    • Sambelashvili AT, Nikolski VP, Efimov IR. Virtual electrode theory explains pacing threshold increase caused by cardiac tissue damage. Am J Physiol Heart Circ Physiol. 2004 Jun;286(6):H2183-94. Epub 2004 Jan 15. PMID: 14726298. [PubMed]
    • Takagi S, Pumir A, Pazo D, Efimov I, Nikolski V, Krinsky V. Unpinning and removal of a rotating wave in cardiac muscle. Phys Rev Lett. 2004 Jul 30;93(5):058101. Epub 2004 Jul 26. PMID: 15323732. [PubMed]
    • Takagi S, Pumir A, Pazo D, Efimov I, Nikolski V, Krinsky V. A physical approach to remove anatomical reentries: a bidomain study. J Theor Biol. 2004 Oct 21;230(4):489-97. PMID: 15363671. [PubMed] [PDF]
    • Efimov IR, Nikolski VP, Salama G. Optical imaging of the heart. Circ Res. 2004 Jul 9;95(1):21-33. PMID: 15242982. [PubMed]

    2003

    • Li L, Nikolski V, Efimov IR. Effects of lidocaine on shock-induced vulnerability. J Cardiovasc Electrophysiol. 2003 Oct;14(10 Suppl):S237-48. PMID: 14760929. [PubMed]
    • Efimov IR, Nikolski VP. Diastolic shocking experience: do virtual electrodes exist only during systole? J Cardiovasc Electrophysiol. 2003 Nov;14(11):1223-4. PMID: 14678139. [PubMed]
    • Dobrzynski H, Nikolski VP, Sambelashvili AT, Greener ID, Yamamoto M, Boyett MR, Efimov IR. Site of origin and molecular substrate of atrioventricular junctional rhythm in the rabbit heart. Circ Res. 2003 Nov 28;93(11):1102-10. Epub 2003 Oct 16. PMID: 14563715. [PubMed]
    • Efimov IR. Fibrillation or neurillation: back to the future in our concepts of sudden cardiac death? Circ Res. 2003 May 30;92(10):1062-4. PMID: 12775654. [PubMed]
    • Efimov IR. Mechanisms of stimulation and defibrillation, Cornell University, NY, March 11, 2003.
    • Sambelashvili AT, Nikolski VP, Efimov IR. Nonlinear effects in subthreshold virtual electrode polarization. Am J Physiol Heart Circ Physiol. 2003 Jun;284(6):H2368-74. PMID: 12742834. [PubMed]
    • Efimov IR. Century of Defibrillation, XII World Congress on Cardiac Pacing & Electrophysiology, Hong Kong, China, February 22, 2003. Pacing Clin Electrophysiol. 2003 Feb;26(2 Pt 2):S1-245. PMID: 12708446. [PubMed]
    • Garrigue S, Reuter S, Efimov IR, Mazgalev TN, Jais P, Haissaguerre M, Clementy J. Optical mapping technique applied to biventricular pacing: potential mechanisms of ventricular arrhythmias occurrence. Pacing Clin Electrophysiol. 2003 Jan;26(1 Pt 2):197-205. PMID: 12687812. [PubMed]
    • Nikolski VP, Jones SA, Lancaster MK, Boyett MR, Efimov IR. Cx43 and dual-pathway electrophysiology of the atrioventricular node and atrioventricular nodal reentry. Circ Res. 2003 Mar 7;92(4):469-75. Epub 2003 Jan 30. PMID: 12600895. [PubMed]
    • Efimov IR, Mowrey KA, Cheng Y, Tchou PJ Letter to editor, EuroPACE, 2003, 5(3): 243-244.